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Immune Cellular Support System™ - Research Citations

Agaricus blazei murrill

Ahn, W.S., D.J. Kim, G.T. Chae, J.M. Lee, S.M. Bae, J.I. Sin, Y.W. Kim, S.E. Namkoong, and I. P. Lee, "Natural killer cell activity and quality of life were improved by consumption of a mushroom extract, Agaricus blazei Murill Kyowa, in gynecological cancer patients undergoing chemotherapy", International Journal of Gynecological Cancer 14(4), (2004), 589-594

Fujimiya, Yoshiaki, Youichi Suzuki, Ko-ichi Oshiman, Hidekazu Kobori, Koichi Moriguchi, Hisako Nakashima, Yonezo Matumoto, Shogo Takahara, Takusaburo Ebina, and Ryuichi Katakura, "Selective tumoricidal effect of soluble proteoglucan extracted from the basidiomycete, Agaricus blazei Murill, mediated via natural killer cell activation and apoptosis", Cancer Immunology, Immunotherapy 46(3), (1998), 147-159

Mizuno, Masashi, Mikio Morimoto, Ken-ichiro Minato, and Hironobu Tsuchida, "Polysaccharides from Agaricus blazei stimulate lymphocyte T-cell subsets in mice", Bioscience, Biotechnology, and Biochemistry 62(3), (1998), 434-437

Aloe vera

Dr. David Frawley and Dr. Vasant Lad, The Yoga of Herbs (Wisconsin: Lotus Press, 2001), 100-101.

Andrographis paniculata

A. Asawamekin, U. Chanchareon, N. Poolsup, S. Prathanturanrug, C. Suthisisang,  “Androgrpahis paniculata in the symptomatic treatment of uncomplicated upper respiratory tract infection: systematic review of randomized controlled trials”, J Clin Pharm Ther  29(1), (2004), 37-45

V. Aguirre, S. Arriagada,  J.C. Bertoglio, R.A. Burgos, D.D. Cáceres, M. Calvo,  J.L. Hancke, “Efficacy of Andrographics paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial”, Clin Rheumatol, 28(8), (2009), 931-46

Astragalus root

Michael Tierra, The Way of Herbs, (New York: Pocket Books, 1980), 223.

B.-M. Shao, W. Xu, "A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb”, Biochemical and Biophysical Research Communications 320(4), (2004), 1103-1111
W. C. S. Cho and K. N. Leung, "In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceus", Journal of Ethnopharmacology 113(1), (2007), 132-141
Z. G. Liu, Z. M. Xiong, and X. Y. Yu, "Effect of astragalus injection on immune function in patients with congestive heart failure", Chinese journal of integrated traditional and Western medicine 23(5), (2003), 351

Atractylodes root

Ron Teeguarden, The Ancient Wisdom of the Chinese Tonic Herbs (New York: Warner Books, 1998), 197, 368.

Chinese lovage (cnidium)

Michael Tierra, The Way of Herbs, (New York: Pocket Books, 1980), 224-225


K. T. Lee, J. Choi, W. T. Jung, J. H. Nam, H. J. Jung, and H. J. Park, “Structure of a new echinocystic acid bisdesmoside isolated from Codonopsis lanceolata roots and the cytotoxic activity of prosapogenins”,  J Agric.Food Chem 50(15), (2002), 4190-4193

Michael Tierra, The Way of Herbs, (New York: Pocket Books, 1980), 226.

Ron Teeguarden, The Ancient Wisdom of the Chinese Tonic Herbs (New York: Warner Books, 1998), 157-159, 358.

Y. Chen, N. Liang, J. Wei, and Y. Zhu, “Chemical components of Codonopsis pilosula (Franch.) Nannf. var. volubilis (Nannf.) L.T. Shen”, 20(10), (1995), 611-640


G. Davison, “Bovine colostrum and immune function after exercise”, Med Sport Sci, (2012)  

H. Arvilommi, F. He, S. Salminen, E. Tuomola, “Modulation of human humoral immune response through orally administered bovine colostrum”, FEMS Immunol.Med.Microbiol 31(2), (2001), 93-96

H. Dichtelmuller, R. Lissner, W. Stephan, “Antibodies from colostrum in oral immunotherapy”, J Clin Chem Clin Biochem 28(1), (1990), 19-23


Christopher Hobbs, Medicinal Mushrooms (California: Botanica Press, 1986), 81-86.


A. H. Chow, K. K. Chu, S. S. Ho, "Coriolus versicolor: a medicinal mushroom with promising immunotherapeutic values", The Journal of Clinical Pharmacology 42(9), (2002), 976-984

Cui, Jian, and Yusuf Chisti, "Polysaccharopeptides of Coriolus versicolor: physiological activity, uses, and production", Biotechnology Advances 21(2), (2003), 109-122


Aisa, Yoshinobu, Yoshitaka Miyakawa, Tomonori Nakazato, Hideyuki Shibata, Kaori Saito, Yasuo Ikeda, and Masahiro Kizaki, "Fucoidan induces apoptosis of human HS‐Sultan cells accompanied by activation of caspase-3 and down-regulation of ERK Pathways", American Journal of Hematology 78(1), (2005), 7-14

Choi, Eun-Mi, Ah-Jin Kim, Yeon-O. Kim, and Jae-Kwan Hwang, "Immunomodulating activity of arabinogalactan and fucoidan in vitro", Journal of Medicinal Food 8(4), (2005), 446-453

Hong, Sang-Won, Hee-Seung Lee, Kyung Hee Jung, Hyunseung Lee, and Soon-Sun Hong, "Protective effect of fucoidan against acetaminophen-induced liver injury", Archives of Pharmacal Research 35(6), (2012), 1099-1105

Itoh, Hiroko, H. Noda, H. Amano, C. Zhuaug, T. Mizuno, and H. Ito, "Antitumor activity and immunological properties of marine algal polysaccharides, especially fucoidan, prepared from Sargassum thunbergii of Phaeophyceae", Anticancer Research 13(6A), (1993), 2045

Lee, Jung-Bum, Kyoko Hayashi, Minoru Hashimoto, Takahisa Nakano, and Toshimitsu Hayashi, "Novel antiviral fucoidan from sporophyll of Undaria pinnatifida (Mekabu)", Chemical and Pharmaceutical Bulletin 52(9), (2004), 1091-1094

Murphy, Vanessa, Syed AM Tofail, Helen Hughes, and Peter McLoughlin, "A novel study of hexavalent chromium detoxification by selected seaweed species using SEM-EDX and XPS analysis", Chemical Engineering Journal 148(2), (2009), 425-433


C. Liu, J. L. Zhu, “Modulating effects of extractum semen Persicae and cultivated Cordyceps hyphae on immuno-dysfunction of inpatients with posthepatitic cirrhosis”, Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi 12(4), (1992), 207-9, 195

Y. Y. Hu, P. Liu, C. Liu, “Effect of fuzheng huayu recipe in treating posthepatitic cirrhosis”, Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi 16(8), (1996), 459-462

Poria cocos

Jose-Luis Rios, “Chemical Constituents and Pharmacolgical Properties of Poria cocos”, Planta Med 77, (2011), 681-691

Michael Tierra, The Way of Herbs, (New York: Pocket Books, 1980), 227.


Christopher Hobbs, Medicinal Mushrooms (California: Botanica Press, 1986), 96-107.


Christopher Hobbs, Medicinal Mushrooms (California: Botanica Press, 1986), 125-138.


B.W. Nichols, and B. JB Wood, "The occurrence and biosynthesis of gamma-linolenic acid in a blue-green alga, Spirulina platensis", Lipids 3(1), (1968), 46-50

E. W. Becker, B. Jakober, D. Luft, and R. M. Schmulling, "Clinical and biochemical evaluations of the alga Spirulina with regard to its application in the treatment of obesity. A double-blind cross-over study", Nutrition Reports International 33, (1986)

Hala N. ElSohly, Mahmoud A. ElSohly, Nirmal, David S. Pasco, Pugh, and Samir A. Ross,  "Isolation of three high molecular weight polysaccharide preparations with potent immunostimulatory activity from Spirulina platensis, Aphanizomenon flos-aquae and Chlorella pyrenoidosa", Planta Medica 67(8), (2001), 737-742

H. N. Chou, C. C. Hsieh, J. J. Hsu, H. K. Lu, and Y. K.Yang, ‘Preventive effects of Spirulina platensis on skeletal muscle damage under exercise-induced oxidative stress”,  Eur J Appl Physiol 98(2), (2006), 220-226

J. Armesto, I. Garcia, R. Gonzalez, N. Ledon,  D. Remirez, C. Romay, “Antioxidant and anti-inflammatory properties of C-phycocyanin from blue- green algae”,  Inflamm.Res  47(1), (1998), 36-41

M. E. Gershwin, T. K. Mao, and J. Van de Water, "Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients", Journal of Medicinal Food 8(1), (2005), 27-30

Parada, J. L., Zulpa, de Caire, Zaccaro de Mule, M. C., and Storni de Cano, M. M. “Lactic acid bacteria growth promoters from Spirulina platensis”, Int J Food Microbiol 45(3), (1998), 225-228

P. Bhadouria, Z. Khan, "Nutritional and Therapeutic Potential of Spirulina", Current Pharmaceutical Biotechnology 6(5), (2005), 373-379

P.C. Bickford, J. Contreras, C.E. Hudson, J.N. Jernberg,  R.L. Klien, J. Morganti, M.M. Pabon,“A Spirulina-Enhanced Diet Provides Neuroprotection in an α-Synuclein Model of Parkinson’s Disease”, PloS One 7(9), (2012), e45256

P. K. Ghosh, S. Mishra, A. Patel, “Antioxidant potential of C-phycocyanin isolated from cyanobacterial species Lyngbya, Phormidium and Spirulina spp”,  Indian J Biochem Biophys  43(1), (2006), 25-31

S. Boussiba, and A. E. Richmond, "C-phycocyanin as a storage protein in the blue-green alga Spirulina platensis", Archives of Microbiology 125(1), (1980), 143-147

T. Inayama, K. Iwata, "Effects of Spirulina platensis on plasma lipoprotein lipase activity in fructose-induced hyperlipidemic rats", Journal of Nutritional Science and Vitaminology 36(2), (1990), 165-171

Zizyphus seed

Michael Tierra, The Way of Herbs, (New York: Pocket Books, 1980), 230.

Ron Teeguarden, The Ancient Wisdom of the Chinese Tonic Herbs (New York: Warner Books, 1998), 196, 368.


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