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Bone-D™ - Research Citations


C. Gennari, “Effect of ipriflavone- a synthetic derivative of natural isoflavones on bone mass loss in the early years after menopause”, Menopause 5, (1998), 9-15

C.L. Dong, J. Du, S.W. Li,  J.F. Wu, X. Zhang, Y.P. Zhang, “Effects of ipriflavone on postmenopausal syndrome and osteoporosis”, Gynecol Endocrinol 11, (2009), 1-5

D. Agnusdei, “A double-blind, placebo controlled trial of ipriflavone for prevention of postmenopausal spinal bone loss”, Calcification Tissue Int’l 61, (1997), 142-7

K. Kitatani, H. Morii, “Ipriflavone”, Nippon Rinsho 56(6), (1998), 1537-43

S. Adami, L. Bufalino, R. Cervetti, C. Di Marco, O. Di Munno, L. Fantasia, G.C. Isaia, U. Serni, L. Vecchiet, M. Passeri, “Ipriflavone prevents radial bone loss in postmenopausal women with low bone mass over 2 years”,  Osteoporosis Int 7(2), (1997), 119-25

S. Benvenuti, “Effects of ipriflavone and its metabolites on a clonal osteoblastic cell line”, J Bone Miner Res 6, (1991), 987-96

Silica-rich bamboo leaf-Silicon

R. Jugdaosingh, “Silicon and Bone Health”, J Nutr Health Aging 11(2), (2007), 99-110

Vitamin D

C. Garland, F. Garland, "Serum 25-Hydroxyvitamin D and Colon Cancer: Eight-Year Prospective Study”, The Lancet 334(8673), (1989), 1176-1178

D. E. Cole, H. M. Trang, "Evidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does vitamin D2", Am J Clin Nutr 68(4), (1998), 854-858

G. Rammos, P. Tseke, "Vitamin D, the renin-angiotensin system, and insulin resistance", International Urology and Nephrology 40(2), (2008), 419-426

Hugo Van Baelen, Roger Bouillon, Marc De Maeyer, Anja Rabijns, Camiel De Ranter, Christel Verboven, “A structural basis for the unique binding features of the human vitamin D-binding protein”, Nature Structural Biology 9(2), (2002), 131-136

J. L. Anderson, H. T. May, "Relation of Vitamin D Deficiency to Cardiovascular Risk Factors, Disease Status, and Incident Events in a General Healthcare Population", The American Journal of Cardiology 106(7), (2010), 963-968

J. Lau, A.G. Pittas, "The Role of Vitamin D and Calcium in Type 2 Diabetes. A Systematic Review and Meta-Analysis", Journal of Clinical Endocrinology & Metabolism 92(6), (2007), 2017-2029

K. Helzlsouer, J.Tangrea, "Serum levels of vitamin D metabolites and the subsequent risk of colon and rectal cancer in Finnish men”, Cancer Causes and Control 8(4),(1997), 615-625

L.A.G. Armas, J. Grote, R.P. Heaney, R.L. Horst, R.R. Recker, “Vitamin D3 is More Potent Than Vitamin D2 in Humans”, Journal of Clinical Endocrinology & Metabolism

Laura A.G. Armas, Bruce W. Hollis and Robert P. Heaney, “Vitamin D2 is much less effective than Vitamin D3 in Humans”, The Journal of Clinical Endocrinology and Metabolism 89(11), (2004), 5387-5391

Lisa A.Houghton, and Reinhold Vieth, "The case against ergocalciferol (vitamin D2) as a vitamin supplement", The American Journal of Clinical Nutrition 84(4), (2006), 694-697

M. F. Holick, “Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease", Am J Clin Nutr 80(6), (2004), 1678S-1688S

M. F. Holick, "Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis", Am J Clin Nutr 79(3), (2004), 362-371

Michael F. Holick, “The Vitamin D Epidemic and its Health Consequences”, J Nutr 135, (2005), 2739S-2748S

M. J. Pencina, T. J. Wang, “Vitamin D Deficiency and Risk of Cardiovascular Disease", Circulation 117(4), (2008), 503-511

Robert P. Heaney, “Lessons for nutritional science from vitamin D”, Am J Clin Nutr 69, (1999), 825-6

Robert P. Heaney, “Vitamin D: Criteria for safety and efficacy”, Nutrition Reviews 66(2), (2008), S178-S181

R. P. Heaney, R. R. Recker, "Vitamin D3 Is More Potent Than Vitamin D2 in Humans", Journal of Clinical Endocrinology & Metabolism 96(3), (2011), E447-E452

U. A. Ajani, E. S. Ford, "Concentrations of Serum Vitamin D and the Metabolic Syndrome Among U.S. Adults", Diabetes Care 28(5), (2005), 1228-1230

Y. Liel, E. Ulmer, "Low circulating vitamin D in obesity", Calcif Tissue Int 43(4), (1988), 199-201

Vitamin K2 (MK-7)

M. Neale Weitzmann, Masayoshi Yamaguchi, “Vitamin K2 stimulates osteoblastogenesis and suppresses osteoclastogenesis by suppressing NF-kB activation”, International Journal of Molecular Medicine, (2010), 3-14


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